Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
نویسندگان
چکیده
منابع مشابه
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1.
In the fasted state, induction of hepatic glucose output and fatty acid oxidation is essential to sustain energetic balance. Production and oxidation of glucose and fatty acids by the liver are controlled through a complex network of transcriptional regulators. Among them, the transcriptional coactivator PGC-1alpha plays an important role in hepatic and systemic glucose and lipid metabolism. We...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2007
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0702509104